摘要
生物转化是碳水化合物资源高效利用的有效途径。利用转糖基酶和异构化酶将现有的丰富的单糖、寡糖、环糊精等转化为功能性稀有糖、寡糖,为食品、医药、新材料等行业提供新的原料,对于社会经济发展具有明显的推动作用。本文综述了转糖基酶、异构化酶的结构、定向进化、催化过程调控策略等方面的最新研究进展,并就该领域面临的科学问题和发展趋势进行了总结和展望,以期对相关领域研究者有所启发。
Biotransformation is the effective approach for full usage of carbohydrate resources.Transglycosylases and isomerases can transform different monosaccharides,oligosaccharides and cyclodextrins naturally existing to functional rare sugars and oligosaccharides,which are novel materials for food,medicine and material industries.This review introduces recent progress in structure characterization and directed evolution of typical transglycosylases and isomerases,the regulation strategies during enzymatic reactions.Scientific issues and the trends of using transglycosylases and isomerases in carbohydrates biotransformation are summarized for providing helpful references to researchers in carbohydrate research.
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2011年第9期36-45,共10页
Journal of Chinese Institute Of Food Science and Technology
关键词
碳水化合物
糖酶
转糖基酶
异构酶
调控策略
carbohydrate
enzyme
transglycosylase
isomerase
regulation strategy
