摘要
目的对山东省内市售红花、五味子、蒲黄、朱砂、血竭五种药材及饮片中非法添加人工合成色素情况进行监督抽验。方法采用国家食品药品监督管理局药品检验补充检验方法和检验项目批准件中的TLC法进行初筛,HPLC-DAD法进一步定性,最后用HPLC-MS法确证。结果红花除部分批次检出标准规定检测的色素金橙Ⅱ外,还有4批检出日落黄;五味子未检出标准中规定检测的色素,但有2批检出日落黄;蒲黄与朱砂部分批次检出标准中规定检测的色素金胺O、808猩红,未检出其他色素;血竭未检出任何色素。结论目前中药材的色素添加情况较为严重,并出现了添加标准规定以外色素的新情况。
Objective To supervise and investigate the adulteration of synthetic pigments in Carthami Flos,Schizandrae Chinensis Fructus,Typhae Pollen,Cinnabaris and Draconis Sanguis.Those five Chinese medicinal materials are sold commonly in Shandong markets.Methods Preliminary screening by TLC method,further qualitation by HPLC-DAD method and confirmation by HPLC-MS method were preformed.Results Orange Ⅱ,which was defined in the standards,was detected from some batches of Carthami Flos and sun set yellow from four batches.No pigment defined in the standards was detected from Schizandrae Chinensis Fructus,but sun set yellow from two batches.Auramine O and 808 Scarlet,which were defined in the standards,were detected from some batches of Typhae Pollen and Cinnabaris.No pigment was detected from Draconis Sanguis.Conclusion It is serious in the adulteration of synthetic pigments in the Chinese medicinal materials and it presents a new problem about adulteration of pigments which were not defined in the standards.
出处
《中国药事》
CAS
2011年第12期1200-1202,共3页
Chinese Pharmaceutical Affairs
关键词
人工合成色素
红花
五味子
蒲黄
朱砂
血竭
synthetic pigment
Carthami Flos
Schizandrae Chinensis Fructus
Typhae Pollen
Cinnabaris
Draconis Sanguis
