摘要
本文观察了25名陈旧性心肌梗塞病人的血小扳聚集性和血浆血栓素B_2水平.血小板聚集性以1.25μmol、2.5μmol ADP和1μmol、2μmol肾上腺素为诱导剂,以1min聚集率、最大聚集率和自发聚集率为指标.结果表明:陈旧性心肌梗塞病人的上述各项指标均高于正常对照组(P<0.01);放射免疫法测定血栓素B_2示:陈旧性心肌梗塞病人的血浆血栓素B_2水平明显高于正常对照组(P<O.01),显示陈旧性心肌梗塞病人存在高凝状态.本文并对影响血小板聚集测定的技术性因素作了探讨.
This paper reports the platelet aggregation and the level of plasma throm-boxane B_2(TXB_2) in patients with old myocardial infarction(OMI). The platelet aggregation was induced by adenosine diphosphate(1.25 μmol, 2.5μmol) and adrenaline (1 μmol, 2 μmol)and the platelet aggregation ratio in the first minute and the maximal platelet aggregation ratio were studied.The results showed that the platelet aggregation described above and the level of plasma TXB_2 in the 25 patients with OMI we treated were significantly higher than those in the control group(P<0.01),revealing a hypercoagulation state in patients with OMI.The technical factors which would affect the platelet aggregation were discussed as well.
关键词
心肌梗塞
血小板凝集
血栓素B2
Myocardial infarction/pathophysiol
Platelet aggregation
Thromboxane B_2/blood
