摘要
目的探讨联合组织学、细胞学与免疫组化法对肺小细胞癌(small cell lung cancer,SCLC)的诊断及鉴别诊断的意义。方法回顾性分析组织学诊断为肺癌,疑为SCLC的42例患者的病理资料,联合观察活检切片和细胞学刷片再配以免疫组化染色,确定分型诊断。结果 42例肺癌患者中,有21例诊断为SCLC,2例诊断为淋巴瘤,19例诊断为低分化鳞状细胞癌。结论上述3种病理学检查方法可优势互补,联合应用于SCLC的诊断和鉴别诊断,可明显提高组织分型的病理诊断水平,减少误诊、漏诊,给临床治疗方案的选择提供重要依据。
Purposes To explore the value of combining routine histological examination, cytology smear and immunohistochemical staining in the diagnosis and differential diagnosis of small cell lung carcinoma （SCLC）. Methods The pathological data of 42 patients were retrospectively analyzed, and were also confirmed as lung cancer which suspected as SCLC in histological elassfication. Basing on the results of biopsy section, cytology smear and immunohistochemical staining, it could eventually get full data of pathological diagnosis and histological classification. Results Among 42 patients with lung cancer, there were 21 cases of SCLC, 2 cases of lymphoma and 19 cases of poor differentiated squamous cell carcinoma by combining those 3 methods in histological classfication. Conclusion Combining application of biopsy section, cytology smear and immunohistochemical staining in diagnosis of SCLC could be complementary each other, and could significantly improve the correct rate of pathological diagnosis and histological classification, which was also valuable in the selection of clinical treatment protocols for clinician.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
2012年第1期61-64,共4页
Chinese Journal of Clinical and Experimental Pathology
关键词
肺肿瘤
小细胞癌
鳞癌
支气管镜活检
细胞学涂片
lung neoplasms
small cell cancer
squamous cell carcinoma
bronchoscopy biopsy
cytology smear
