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肺结核发病及结核菌素试验与卡介苗接种的关系探讨

Study on correlation of pulmonary tuberculosis, tuberculous vaccine test and vaccination of Bacillus Calmette-Guerin.
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摘要 对1984~1988年入学的3968名大学生进行了五年随访、观察,发现大学生的结核病发病率以入学时结核菌素试验呈阴性反应并接种了卡介苗组最低(为0)。试验呈强阳性反应者的发病率(35.4‰)明显高于阳性反应组(5.43‰)。而阴性反应者因故未接种卡介苗的,其发病率较强阳性反应组还高(333‰),各组发病率之间均有非常显著的差异(p<0.001)。说明做好入学新生结核菌素试验测定,对易感人群即阴性者进行卡介苗接种,并对强阳性反应者和新发病人加强管理,是控制大学生结核病疫情的有效措施。 3768 students of our university have been investigated in following tracks of them for five years, who admitted into Our university during 1984 to 1988. The result of observation showed that' the pulmonary tuberculosis ( TB ) occurring rate of students is the lowest (its value is zero) , who not only presented negative reaction in tuberaclous vaccine test when they just admitted into university but also were vaccinated with Bacillus Calmette-Guerin)BCG ) .But the TB occurring rate of students presented strong positive reaction ( its value is 35.40 ‰ ) is eventually higher than positive reaction's (its value is 5.43 ‰), and negative reaction's of not vaccinating with BCG for some reasons is higher than the strong positive reaction's (its value is 333‰ ) .The difference among the rate of above are quite evident ( p < 0.001) . Therefore, it is necessary for every student of admittance to be made the tuberculous vaccine test, and vaccinated with BCG for the crowd infected easily by tuberculosis vaccine ( presented negative reaction ) . And the management of students presented strong positive reaction and new patients with TB should be strengthened. This is an effective measurment to control the epidemic situation of TB of students.
作者 沈林生
机构地区 浙江农业大学
出处 《浙江农业大学学报》 CSCD 1990年第4期441-443,共3页
关键词 结核病 发病率 结核菌素试验 pulmonary tuberculosis occurring rate tuberculous vaccine test Bacillus Calmette-Guerin students
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