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响应面分析法优化葛根中异黄酮提取工艺 被引量:11

Optimization of Extraction Technology of Isoflavones from Pueraria lobata by Response Surface Analysis Methodology
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摘要 目的:优选葛根中异黄酮的提取工艺。方法:以葛根异黄酮为评价指标,通过响应面分析法优化葛根异黄酮的提取工艺,并对最佳提取工艺进行工艺验证。结果:葛根异黄酮的最佳提取工艺为65%乙醇,超声提取28 min,料液比1∶29,异黄酮的提取率可达4.87%。结论:采用响应面分析法优化对葛根异黄酮提取条件进行优化合理可行。 Objective:To optimize of extraction technology for isoflavones from Pueraria lobata.Method:Optimization of extraction technology for isoflavones from P.lobata by response surface analysis method with isoflavones from P.Lobata as index,and verification of optimum extraction technology.Result:Optimal extraction technology was as follows: ethanol concentration 65%,ultrasonic extraction time 28 min,solid-liquid ratio 1∶29,extraction ratio of isoflavones could be up to 4.87%.Conclusion:It was feasible to optimize extraction processing of isoflavones from P.lobata by response surface analysis methodology.
出处 《中国实验方剂学杂志》 CAS 北大核心 2012年第2期45-48,共4页 Chinese Journal of Experimental Traditional Medical Formulae
关键词 响应面 葛根 异黄酮 提取工艺 response surface methodology Pueraria lobata isoflavones extraction technology
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  • 1李文,贺殿,王晓,赵原.葛花中总黄酮的含量测定[J].西北药学杂志,2005,20(1):14-15. 被引量:15
  • 2陈玉昆.中药提取生产工艺学[M].沈阳:辽宁出版社,1992.
  • 3MIAO H. The pharmacological action of compounds of isoflavone[J]. Foreign Med Sci-Sec Pharmacol, 1999, 16: 355-358.
  • 4HAN YO, HAN M J, PARK S H, et al. Protective effects of kakkalide from flos puerariae on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora[J]. Journal of Pharmacological Sciences, 2003, 93:331-336.
  • 5LEE H U, BAIE E A, KIM D H. Hepatoprotective effects of tectoridin and tectorigenin on tert-buty hyperoxide-induced liver injury[J]. Journal of Pharmacological Sciences, 2005, 97:541-544.
  • 6FAG R, HOUGHTON P J, HYLANDS P J. Cytotoxic effects of compounds from Iris tectorum on human cancer cell lines[J]. J Ethnopham Acol, 2008, 118(2): 257-263.
  • 7YOU K M, JONG H G, KIM H P. Inhibition of cyclooxygenase/ lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants[J]. Arch Pharm Res, 1999, 22 (1): 18-24.
  • 8KANG K A, ZHANG R, HAO M J. Protective effect of irisolidone,a metabolite of kakkalide, against hydrogen peroxide induced cell damage via antioxidant effect[J]. Bioorganic & Medicinal Chemistry, 2008, 16: 1133-1141.
  • 9DIMITROV K, METHEVA D, BOYADZHIEV L. Integrated process of extraction and liquid membrane isolation of atropine from Atropa belladonna roots[J]. Separation and Purification Technology, 2005, 46:41-45.
  • 10BOYADZHIEV L, DIMITROV K, METCHEVA D. Integration of solvent extraction and liquid membrane separation: an efficient tool for recovery of bioactive substances from botanicals[J]. Chemical Engineering Science, 2006, 61: 4126-4128.

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