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左氧氟沙星四联疗法根除幽门螺杆菌感染疗效观察 被引量:5

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摘要 目的观察左氧氟沙星短程四联疗法根除幽门螺杆菌(Hp)感染的疗效。方法 160例Hp阳性病人慢性胃炎和消化性溃疡患者,随机分为两组。治疗组采用雷贝拉唑10mg,阿莫西林1000mg,左氧氟沙星0.2g,呋喃唑酮0.2g,口服,均每日2次,疗程一周;对照组采用雷贝拉唑10mg,阿莫西林1000mg,克拉霉素0.5g,口服,均每日2次,疗程一周,停药1个月后,应用14C-UBT法检测Hp的根除率。结果治疗组根除率为95%明显高于对照组根除率75%,P<0.05。结论雷贝拉唑、阿莫西林、左氧氟沙星、呋喃唑酮四联疗法的Hp根除率高,毒副作用小,是根除Hp的理想方案,值得推广。
出处 《现代消化及介入诊疗》 2011年第6期384-385,共2页 Modern Interventional Diagnosis and Treatment in Gastroenterology
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  • 1马东礼,孙国娣,范珍妮,陆德源.幽门螺杆菌甲硝唑纸片法药敏试验标准化的探索[J].中华检验医学杂志,2004,27(6):386-387. 被引量:5
  • 2虎月燕,周曾芬,南琼,蒋海燕,张磊,李晓燕,段丽萍,陈娅蓉.云南省三个民族人群幽门螺杆菌甲硝唑耐药调查[J].中华流行病学杂志,2004,25(11):986-988. 被引量:14
  • 3史碧山,佘菲菲,林赛榕,潘玉凤,江勇.幽门螺杆菌检测法比较及药敏试验[J].中华消化内镜杂志,1997,14(1):26-28. 被引量:60
  • 4Cagrita J,Oleastro M, Matos R, et al. Features and Trends in Helicobacter Pylori Antibiotic Resistance in Lisbon area, Portugal(1990-1999)[J]. Journal of Antimicrobial Chemotherapy, 2000,46 : 1029-1031.
  • 5Duck W M,Sobel J ,Pruckler J M,et al. Antimicrobial Resistance Incidence and Risk Factors Among Helicobacter Pyloriinfected Persons, United States[J]. Emerg Infect Dis, 2004,10 (6) : 1088-1094.
  • 6Boyanoval L,Mentis A,Gubina M,et al. The Status of Antimicrobial Resistance of Helicobacter Pylori in Eastern Europe [J].Clinical Microbiology and Infection,2002,8(7) :388-396.
  • 7Wu H,Shi X D,Wang H T,et al. Resistance of Helicobacter Pylori to Metronidazole, Tetracycline and Amoxycillin [J]. Journal of Antimicrobial Chemotherapy,2000,46:121-123.
  • 8Glupczynski Y,graud Me, Lopez-Brea I.,et al, European Multcentre Survey of in Vitro Antimicrobial Resistance in Helico bacter pylori[J]. Eur J Clin Microbiol Infect Dis, 2001,20 : 820-823.
  • 9Vicente R,Sicilia B,Gallego S,et al, Helicobacter Pylori Eradication in Patients with Peptic Ulcer after two Treatment Fail ures: a Prospeclive Culture-guided Study[J]. Gastroentero Hepatol,2002,25(7):138-442
  • 10Xia H X, Keane C T, Beatties S, et al. Standardization of Disk Diffusion Test and hs Clinical Significance for Susceptibility Testing of Metronidazole Against Helicobacter Pyloni[J]. Antimicrobial Agents and Chemotherapy, 1994, 38 (10) : 2357-2361.

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  • 1陈淑萍,王磊,余建奎.益生菌联合三联疗法根除幽门螺杆菌的临床研究[J].中华临床感染病杂志,2012,5(2):98-100. 被引量:42
  • 2袁媛,于静,贾长河.含左氧氟沙星的一线方案根除幽门螺杆菌疗效分析[J].山东医药,2009,49(52):96-97. 被引量:2
  • 3张芳,陈安进,石杰,孙樱,刘吉勇,钟慧闽,汪肃文.利福昔明治疗急性感染性腹泻111例临床疗效及安全性[J].中国新药与临床杂志,2005,24(10):781-784. 被引量:3
  • 4缪晓辉.对感染性腹泻的新认识[J].中华传染病杂志,2006,24(4):217-219. 被引量:40
  • 5陈诗华,刘伟,倪广婷,等.左氧氟沙星替代标准三联中的阿莫西林或克拉霉素治疗幽门螺杆菌感染临床观察.江西省第四次中西医结合消化系统疾病学术交流会论文汇编.2011:140-142.
  • 6Gisbert JP, Gisbert JL, Marcos S, et al. Helicobacter pylori first- line treatment and rescue options in patients allergic to penicillin. Aliment Phammcol Ther, 2005,22(10) :1041-1046.
  • 7De Francesco V, Zullo A, Hassan C, et al. Two new treatment regimens for Helicobacter pylori eradication: a randomised study. Dig Liver Dis, 2001,33 (8) :676-679.
  • 8Vaira D, Zullo A, Vakil N, et al. Sequential therapy versus stand- ard triple-drug therapy for Helicobacter pylori eradication: a ran- domized trial. Ann Intern Med, 2007,146 (8) :556-563.
  • 9Park HG, Jung MK, Jung JT, et al. Randomised clinical trial: a com- parative study of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori infection in naive patients. Al- iment Pharmacol Ther, 2012,35(1):56--65.
  • 10Tursi A, Elisei W, Giorgetti G, et al. Efficacy, tolerability, and fac- tors affecting the efficacy of the sequential therapy in curing Heli- cobacterpylori infection in clinical setting. J Investig Med, 2011,59 (6):917-920.

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