摘要
目的探讨结直肠癌伴肠系膜肿瘤结节对患者预后的影响。方法回顾性分析124例结直肠癌患者临床资料,分为肠系膜肿瘤结节组16例和不伴有肠系膜肿瘤结节组108例,两组患者均进行Dukes'分期,对比分析生存率并评价预后。结果肠系膜肿瘤结节组患者总5年生存率为31.25%,不伴有肠系膜肿瘤结节组为75.00%,两组比较,差异有统计学意义(P<0.05)。肠系膜肿瘤结节组患者在Dukes'A期、B期5年生存率分别为0%和50.0%,不伴有肠系膜肿瘤结节组分别为93.99%和93.18%,差异均有统计学意义(P<0.05),肠系膜肿瘤结节组患者在Dukes'C期、D期5年生存率分别为50.00%和14.29%,不伴有肠系膜肿瘤结节组分别为67.57%和8.33%,两组比较,差异无统计学意义(P>0.05)。伴有肠系膜肿瘤结节患者的Dukes'A+B期患者5年生存率为50.0%,与Dukes'C期67.57%比较,差异无统计学意义(P>0.05)。结论结直肠癌伴有肠系膜肿瘤结节患者预后不良,其临床意义更类似于淋巴结转移。
Objective To investigate the clinical significance of mesenteric tumor nodules in patients with colorectal carcinoma.Methods The clinic and patholgic data of 124 cases with colorectal malignant lesions were analyzed retrospectively.Dukes ＇staging was standardized by considering mesenteric tumor nodules（MTN）separately.Survival analysis were employed to find out the relationship between prognosis and MTN.Results Between groups with and without MTN,the overall survival of 5 years was 31.25%% vs.75.00%（P〈0.05）.Dukes ＇A stage was 0% vs.93.99%%（P〈0.05）,B stage 50.00% vs.93.18%（P〈0.05）,Cstage 50.00% vs.67.57%（P〈0.05）,D stage 14.29% vs.8.33%（P〉0.05）.Dukes ＇A and B stage cases w ith MTN had a similar 5 years overall survival with that of Dukes ＇C stage patients（50.00% vs.67.57%,P〉0.05）.Conclusions Patients with colorectal carcinoma combing with MTN present a worse prognosis,and the significance of MTN may be similar to that of lymph node metastasis.
出处
《医药论坛杂志》
2011年第21期88-89,共2页
Journal of Medical Forum
关键词
结直肠肿瘤
肠系膜
淋巴转移
预后
Colorectal cancer
Mesentery
Lymphatic metastasis
Prognosis
