摘要
目的探讨N-末端脑钠肽前体(NT-proBNP)对心源性和肺源性呼吸困难的鉴别诊断价值。方法用酶免疫分析法测定128例呼吸困难患者血浆中NT-proBNP水平,包括心源性呼吸困难和肺源性呼吸困难,观察两组患者血浆NT-proBNP的水平。同时测定20例健康体检者的NT-proBNP水平作为对照组做比较分析。结果两组患者的血浆NT-proBNP水平,心源性呼吸困难组(1372.68±944.98)ng/L明显高于肺源性呼吸困难组(586.00±85.00)ng/L,两组差异有统计学意义(P<0.05)。结论 NT-proB-NP可作为鉴别心源性呼吸困难和肺源性呼吸困难的一个客观指标,其方法简单迅速、特异性好、敏感性高,具有很高的临床意义。
Objective To investigate the value of NT-proBNP in the differential diagnosis of dyspnea caused by heart disease and pulmonary disease.Methods The NT-proBNP of patients suffered from dyspnea which caused by heart failure or pulmonary disease were measured by immunoenzyme assay.Choosing 20 health cases as the control group and measuring their plasma NT-proBNP level.Results The NT-proBNP level of patients with dyspnea caused by heart disease（1372.68±944.98）ng/L was obviously higher than those patients with dyspnea caused by pulmonary disease（586.00±85.00）ng/L,there were significant differences between the two groups（P〈0.05）.Conclusion NT-proBNP which has remarkable clinical significance can be used as the indicator in the differential diagnosis of dyspnea because of its highly sensitivity and specificity.
出处
《中外医学研究》
2011年第36期39-40,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
