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高龄患者前列腺特异抗原水平与活动性季节性关系研究

Studies on the relationship between the serum PSA level and the seasonality,mobility in elderly male
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摘要 目的探讨高龄患者前列腺特异抗原(PSA)水平与活动性、季节性关系的改变。方法选择门诊或住院患者283例分为4组,将年龄31~40岁的20例为青年组;年龄>80岁的263例,根据活动情况分为卧床组28例,活动弱组86例,活动强组149例。另选择高龄患者52例查四季PSA水平。结果与青年组PSA水平(2.03±0.88)ng/ml比较,高龄患者血清中PSA水平(4.03±2.61)ng/ml显著升高(P<0.01),并且卧床组为(6.14±.36)ng/ml、活动弱组为(4.85±2.41)ng/ml、活动强组为(4.25±2.35)ng/ml,各组间的血清中PSA水平随活动程度的增加而降低,差异有统计学意义(P<0.05)。高龄患者PSA水平在春季(4.86±2.20)ng/ml和秋季(4.97±2.21)ng/ml较夏冬两季[(3.91±1.51)ng/ml,(3.96±1.64)ng/ml]明显增高,差异有统计学意义(P<0.05,P<0.01)。结论由于老年人随年龄的增长,前列腺功能的减退,血清PSA水平具有上升的趋势。检测高龄活动性及季节性PSA水平对临床诊断具有较好的应用价值。 Objective To investigate the relationship between the serum PSA level and the seasonality,mobility in elderly male.Methods Up to 283 patients including inpatients and outpatients were recruited and patients ages between 30 to 40 were regarded as young group.According to mobility,patients over 80 were divided into lying bed group,low mobility group and high mobility group.The PSA level of 52 patients was also detected during different seasons.Results The serum PSA level of the elderly male(4.03±2.61)ng/ml were higher than that in young group(2.03±0.89)ng/ml,(P0.01),and the serum PSA level decreased with the increasing mobility(P0.05).Serum PSA level in different season showed that Serum PSA level increased in spring(4.84±2.20)ng/ml and autumn(4.97±2.21)ng/ml while decreased in summer(3.91±1.55) ng/ml and winter(3.96±1.64)ng/ml,(P0.05,P0.01).Conclusions The prostate function of the elderly male decreased and the serum PSA level increased with the increasing age.Detecting the serum PSA level in different maobility and season has helpful value in clinical diagnosis.
出处 《中华保健医学杂志》 2011年第6期491-492,共2页 Chinese Journal of Health Care and Medicine
关键词 前列腺特异抗原 高龄 活动性 季节性 PSA Eldest age Mobility Seasonality
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