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甘精胰岛素联合格列美脲用于老年2型糖尿病患者效果观察 被引量:9

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摘要 目的探讨甘精胰岛素联合格列美脲用于老年2型糖尿病的效果及安全性。方法将100例口服降糖药物控制不佳的老年2型糖尿病患者随机分为观察组和对照组各50例。观察组每日1次早餐前口服格列美脲,每晚22时注射甘精胰岛素1次;对照组每日早、晚餐前分别注射优泌林70/30。均以空腹血糖5.0~7.0 mmol/L、餐后血糖6.0~10.0 mmol/L为治疗目标,共治疗16周;治疗期间根据血糖情况调整剂量。观察血糖水平及血清C肽水平和低血糖发生情况。结果治疗16周两组全天血糖谱均明显下降,C肽水平均明显升高(P均<0.05);观察组低血糖事件、胰岛素用量、体质量增加均明显少于对照组,P均<0.05。结论甘精胰岛素联合格列美脲用于老年2型糖尿病不仅降糖效果好,且较为安全。
出处 《山东医药》 CAS 北大核心 2011年第47期84-85,共2页 Shandong Medical Journal
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同被引文献48

  • 1陈莉丽,张巾超.改善B细胞功能与持久稳定控制血糖临床实施误区及对策[J].实用糖尿病杂志,2005,13(1):6-8. 被引量:4
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