摘要
目的 探索应用丝裂霉素C降低翼状胬肉手术后复发率的最佳给药方式。方法 10 5例原发性翼状胬肉分为 3组 ,术中及术后以不同浓度给药随访 6～ 12月。结果 3组复发率均低于文献报道中未用药的复发率。术中使用 0 1mg/ml丝裂霉素C组复发率明显低于术后同浓度滴眼组 ,并发症明显少于术后 0 2mg/ml的滴眼组。结论 术中使用低浓度丝裂霉素C是较为有效安全而简便的给药方式。
Objective To research using safely and vatidly mitomycin C to reduce the recurrence rate of pterygium excision.Methods 105 patients of primary pterygium were divided into three groups at random with of different concentration of mitomycin C by intra and post postoperation.The mean following up was 6～12 months.Results The recurrence rates of three groups were lower than those without using mitomycin C in some reports.The recurrence rates of intraoperative 0.1 mg/ml mitomycin C in the excision was lower than that of topical mitomycin C 0.1 mg/ml following excision,and the complication rate was lower than that of topical mitomycin C 0.2 mg/ml following excision obviously ( P < 0.05). Conclusions Intraoperative lower concentration mitomycin C appears to be a more effective and safe treatment to reduce the recurrence rate of pterygium excision.
出处
《眼外伤职业眼病杂志》
北大核心
2000年第1期66-67,共2页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
关键词
丝裂霉素C
翼状胬肉
切除术
复发率
Mitomycin C Pterygium Excision Recurrence Complication.
