摘要
丹参为我国民间常用中药,具有祛瘀止痛、养血安神的功效,现代药理研究其具有扩张冠状动脉、抗感染、改善心、肺、肝的缺血再灌损伤及调节免疫应答等药理作用。其主要抗肿瘤活性成分为丹参酮及其衍生物,本篇主要综述丹参酮ⅡA的抗癌作用及其机制。
Salvia miltiorrhiza was one of the most commonly used folk medicines. Pharmacological effects of its dry roots and rhizomes were revised as removing stasis pain, nourishing sedative, dilating coronary arteries, anti-infection, improving heart,lung,liver ischemia reperfusion injury and regulating the immune response and so on. The main antitumor components were tanshinone and its derivatives. This review discussed the anti-cancer activity of Tanshinone Ⅱ A and its mechanism.
出处
《天然产物研究与开发》
CAS
CSCD
2011年第B12期280-284,共5页
Natural Product Research and Development
关键词
丹参
丹参酮ⅡA
抗癌
Salvia mihiorrhiza
tanshinone ⅡA
anticancer