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窒息新生儿的脑肾血流动力学 被引量:8

Hemodynamics of Cerebrum and Renes in Asphyxiated Neonates.
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摘要 研究新生儿窒息脑、肾损伤及功能障碍的机理,提供早期诊断的敏感方法。【方法】 应用Ultram ark - 9 型彩色多普勒超声仪对窒息新生儿脑与肾动脉的血流动力学参数进行有对照组的前瞻性动态研究。【结果】 新生儿窒息后脑、肾血液灌流阻力增大,血液灌流量减少,尤以舒张期为甚。并发现肾血流动力学紊乱的程度重于脑,且恢复较慢。【结论】 血流动力学紊乱,血流量尤其舒张期血流量减少是新生儿窒息脑、肾损伤的主要原因;运用脉冲多普勒超声观察其血流动力学变化,可用于新生儿窒息脑、肾损伤的早期诊断。 Objective To explore the pathogenesis of cerebral and renal injury in neonates with birth asphyxia,and to offer early diagnostic methods. Methods The authors prospectively and dynamicly observed the variation of hemodynamics of cerebral and renal arteries in asphyxiated neonates and healthy controls by using an Ultramark-9 echocardiography. Results The blood perfusion resistance was increased and the blood flow perfusion was decreased,especially in diostolic period.Futhermore,the hemodynamic disturbance was more severe in renes than that of cerebrum in the same conditions. Conclusion The hemodynamic disturbance was the main reason for cerebral and renal injury and dysfunction in infants with birth aspyxia,and it can be an early diagnostic method to evaluate the organ's injury by using pulsed Doppler ultrasonography to observe the variation of hemodynamics in asphyxiated neonates.
作者 刘敬 曹海英
机构地区 北京市燕化医院
出处 《中国儿童保健杂志》 CAS 2000年第1期3-4,18,共3页 Chinese Journal of Child Health Care
关键词 血流动力学 多普勒超声 新生儿窒息 Asphyxia, Neonatorum, Hemodynamics, Pulsed Doppler ultrasound, Cerebrum, Renes.
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参考文献4

  • 1DrgdsO,GreisenG,LouA,etal.Vasoparalysisassociatedwithbraindamageinasphyxiatedterminfants.JPediatr,1990,117(1):129~131.
  • 2RobillardJE,NakamuraKT,MathemeGP,etal.Renalhemodynamicsandfunctionadjustmenttopastnatallife.Seminporinatol,1988,12(2):145~146.
  • 3LivesP,TalvikR,TalvikT.Changesindopplerultrasonographyinasphyxiatedterminfantswithhypoxic-ischaemicencephalopathy.ActaPaediatr,1998,87:680~681.
  • 4AkinbiH,AbbasiS,PamelaL,etal.Gastrointestinalandrenalbloodvelocityprofileinneonateswithbirthasphyxia.JPediatr,1994,125:625~627.

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