摘要
目的:探讨反复自然流产患者支原体感染趋势及耐药情况。方法:收取2008年8月～2011年8月我院妇产科门诊反复自然流产患者604例(观察组)和同期604例要求人工流产的健康孕妇(对照组),对其进行宫颈分泌物支原体培养和药敏试验。结果:观察组解脲支原体(Uu)、人型支原体(Mh)和Uu+Mh混合感染的总感染率为56.95%(344/604),对照组总感染率为7.28%(44/604),观察组明显高于对照组(P<0.01)。喹诺酮类药物、大环内酯类药物耐药率较高,强力霉素、交沙霉素、美满霉素耐药较低。结论:反复自然流产患者支原体感染率较高,药物治疗应以试验为依据合理用药。
Objective：To discuss the mycoplasma infection and its drug resistance of patients with recurrent spontaneous abortion.Methods：604 patients with recurrent spontaneous abortion（observation group） and 604 healthy pregnant women（control group） who asked for induced abortion at the same period in the maternity clinic of our hospital from August 2008 to August 2011 were included.The culture of mycoplasma cervical secretion and drug resistance test were performed.Results：The total infection rate of Ureaplasma urealyticum（Uu）,Mycoplasma hominis（Mh） and mixed infection（Uu＋Mh） was 56.95%（344/604）,significantly higher than that in the control group of 7.28%（44/604）（P〈0.01）.Moreover,it showed high drug resistance rate of Quinolones,Macrolides and the low rate of Doxycycline,Josamycin,Minocycline Resistance.Conclusion：Mycoplasma infection in patients with recurrent spontaneous abortion is high and drug therapy should be based on the rational drug tests.
出处
《中国医药导报》
CAS
2011年第36期90-91,共2页
China Medical Herald
关键词
自然流产
支原体
耐药分析
Spontaneous abortion
Mycoplasma
Drug resistance
