摘要
目的:探讨妈富隆及己烯雌酚联合安宫黄体酮分别用于治疗青春期功能失调性子宫出血(功血)的效果以及治疗效果与子宫内膜厚度的关系。方法:选择2009年1月～2010年10月收治的青春期功血患者137例,将其分为妈富隆组(治疗组)70例和己烯雌酚联合安宫黄体酮组(对照组)67例。治疗后比较两组患者的控制出血时间、总有效率、血红蛋白、贫血发生率及子宫内膜厚度的变化情况。结果:治疗组患者的总有效率与对照组比较差异无统计学意义(P>0.05)。但与对照组相比,治疗组的止血时间短于对照组、血红蛋白的变化情况优于对照组,贫血发生率低于对照组。差异均有统计学意义(P<0.05)。治疗后两组患者子宫内膜的厚度较治疗前明显变薄,治疗组子宫内膜的厚度较对照组薄(P<0.05)。结论:两种治疗青春期功血均可达到近期治愈的目的,但治疗效果不尽相同,妈富隆治疗功血有显著疗效,且子宫内膜改变更明显,其变化与其他指标结果相符。功血的治疗的效果主要依赖于控制患者出血的时间、贫血情况的改善、总有效率,但子宫内膜的厚度在功血的治疗中也起着一定的作用,子宫内膜厚度在功血治疗中不仅可以指导制定治疗方案,也可作为辅助参考指标,但不能作为唯一或主要的指标。
Objective：To explore the therapeutic effect of Marvelon and Diethylstilbestrol combined with Medroxyprogesterone acetate in treating puberty dysfunctional uterine bleeding and the relationship between endometrial thickness and the effect.Methods：137 patients with adolescent dysfunctional uterine bleeding were selected from January 2009 to October 2010.All cases were divided into Marvelon group（treatment group,70 cases） and Diethylstilbestrol combined with Medroxyprogesterone acetate group（control group,67 cases）.After treatment,bleeding time,the total efficiency,hemoglobin,anemia and the incidence of endometrial thickness changes were observed.Results：Compared with the control group,the total efficiency of treatment group had no significant difference（P〉0.05）.Compared with the control group,bleeding time in treatment group was significantly shorter,changes of hemoglobin were significantly better,and the incidence of anemia was significantly lower,and the differences between the two group was statistically significant（P〈0.05）.After treatment,endometrial thicknesses of all cases were significantly thinner.Conclusion：The two methods can be reached the purpose of healing both;however,the effects are difference.Marvelone has a rather effective in treating adolescent pubery dysfunctional uterine bleeding;the changes of endometrial thicknesses are more evidence,the change is consistent with other indicators.The treatment of uterine bleeding is depended on the effect of the time patients to control bleeding time,anemia improved,and the total efficiency.However,the thickness of the endometrium plays a role in the treatment of DUB.But endometrial thickness in the treatment of dysfunctional uterine bleeding can not only guide the development of treatment programs,but also can be used as a supplementary reference to the womb and not as an only sole or main indicators.
出处
《中国医药导报》
CAS
2011年第36期45-47,共3页
China Medical Herald
关键词
子宫内膜
青春期功能失调性子宫出血
治疗
Endometrial
Adolescent pubery dysfunctional uterine bleeding
Treatment
