摘要
目的 评价MRI诊断脊髓亚急性联合变性(SCD)的价值。方法 7例维生素B12缺乏而临床怀疑SCD的患者进行了MR扫描。扫描包括矢状面T1WI和矢状面、轴面T2WI,其中4例行钆喷替酸葡甲胺(GdDTPA)增强扫描,4例于治疗后行MRI复查。结果 所有病例的T2WI均显示颈髓或胸髓后索高信号病灶,有4例同时出现侧索病灶,T1WI未见异常,GdDTPA增强扫描无强化。有4例在维生素B12治疗后半年及1年4个月复查MRI,T2WI示脊髓后索或侧索高信号病灶明显缩小,与临床表现及实验室检查呈明显正相关。结论 MRI有助于SCD的诊断,且可随访观察维生素B12的治疗效果。
Objective Toanalyzethemagneticresonance (MR)findingsinpatientswithsubacute combineddegeneration (SCD)ofthespinalcord .Methods SevenpatientswithvitaminB12deficiencywhowere clinicallysuspectedtohaveSCDunderwentcervicalorthoracicspinalMRstudy .MRimagingincludedsagittalT1weightedimageandT2 weightedimage,andaxialT2 weightedimage.Fourofthepatientswerescannedafter Gd DTPAenhancementintravenously .Results T2 weightedimagesshowedhighsignalintensityinthedorsal columnsofthecervicalorthoracicspinalcordinallcases,andhighsignalintensityinthelateralcolumnsofthe cervicalorthoracicspinalcordinfourofthesevencases,therewasnoabnormalfindinginT1weightedimages , andnoenhancementafteradministrationofGd DTPA .Thefollow upMRimagingat 6and 16monthsrespectively in 4patientswhohadimprovedclinicalstatusaftervitaminB12 therapydemonstratedthatthehighsignalintensity ofT2 weightedimagesinthedorsalcolumnsofthespinalcordwasdefinitelyreduced ,whichcorrelatedwiththe clinicalstatusandlaboratoryexaminations.Conclusion MRfindingscorrespondwithdemyelinationofthedorsal columnsandlateralcolumnsofthespinalcordinSCD .
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2000年第1期40-42,共3页
Chinese Journal of Radiology
关键词
脊髓疾病
维生素B12缺乏
磁共振成像
Spinalcorddisease
VitaminB12deficiency
Magneticresonanceimaging
