摘要
随着后基因组时代的到来,"组学"成为生命科学研究领域的热点,并在中医药领域也得到了较为广泛的应用。作者从中医证候的宏观角度出发,对基因组学、蛋白质组学、代谢组学等技术在中医疾病证候分类中的应用进行了系统性、规范性的文献研究,探讨中医疾病证候与组学的相关性及其意义。作者指出证候与组学的相关性研究任重而道远,对实现中医辨证论治的科学化和定量化具有重大的临床意义。
As the post-genome era is approaching, omics has become a hot topic in the research field of life sciences and is also widely used in traditional Chinese medicine (TCM) research. For discussing the correlation between syndromes and omics, the authors explored the application of genomics, proteomics and metabonomics in the study of syndrome classification from the macroscopic view, after a systematic and normative study of the literature. The authors drew the conclusion that research into the correlation between syndromes and omics has great clinical significance in terms of the scientific application and quantification of TCM treatment based on syndrome differentiation.
出处
《中西医结合学报》
CAS
2011年第12期1286-1291,共6页
Journal of Chinese Integrative Medicine
基金
国家自然科学基金重大研究计划面上项目(No.90709038)
心脑血管疾病中药新药临床评价技术平台及规范研究(No.2008ZX09312-001)
教育部新世纪优秀人才计划(No.NCET-09-0900)联合资助