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心脏增强磁共振成像评价临床患者心肌活性的实验研究 被引量:2

Identification of viable myocardium with contrast-enhanced magnetic resonance imaging and comparison with other imaging methods
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摘要 目的:评价磁共振成像(MRI)对陈旧性心肌梗死(old myocardial infarction,OMI)患者心肌活性的诊断价值。方法:分析13例OMI患者的增强磁共振(contrast enhanced magnetic resonance ima-ging,ceMRI)延迟强化透壁率、冠状动脉造影TIMI分级结果和心肌双核素显像(single-photon emissioncomputed tomography,SPECT)心肌存活情况。将13例OMI患者ceMRI透壁率、冠状动脉造影TIMI分级和SPECT心肌存活情况进行受试者工作曲线(ROC)分析。结果:ceMRI透壁率曲线下面积为0.953,冠状动脉造影TIMI分级曲线下面积为0.935,ceMRI透壁率与金标准心肌双核素显像相比,透壁率在26%~50%诊断存活心肌的灵敏度为88.9%,特异度为82.7%;透壁率在51%~75%诊断存活心肌的灵敏度为74.1%,特异度为98.7%,与心肌双核素显像相比其诊断的准确性较高。结论:增强MRI清晰显示心肌梗死的位置、范围和程度。ceMRI透壁率诊断存活心肌的准确性较高。 Objective:The aim of this study was to investigate the feasibility and accuracy of the ceMRI to detect the viable myocardium.Methods:In 13 OMI patients analyze ceMRI,TIMI results of coronary angiography and myocardial viability score of SPECT.Determining the diagnostic accuracy of the ceMRI and TIMI by receiver operating characteristic curve(ROC) analysis.Results:The area under the curve(AUC) of transmural ratio with ceMRI was 0.953 and AUC of TIMI was 0.935.The sensitivity and specificity of transmural ratio 26%-50% to detect viable myocardium were 88.9% and 82.7% respectively.The sensitivity and specificity of transmural ratio 51%-75% to detect viable myocardium were 74.1% and 98.7% respectively.Conclusion:Contrast-enhanced MRI can clearly display the location,dimension and extention of myocardial infarction.The accuracy of the ceMRI to detect viable myocardium was very high.
出处 《心肺血管病杂志》 CAS 2011年第6期511-513,共3页 Journal of Cardiovascular and Pulmonary Diseases
关键词 增强磁共振 透壁率 心肌双核素显像 心脏疾病 Contrast-enhanced MRI Transmural ratio Myocardial metabolic single-photon emission computed tomography Heart disease
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