摘要
目的观察土茯苓配方颗粒对临床主要致病菌的抗菌效果。方法采用美国临床实验室标准化委员会(CLSI/NCCLS)推荐的液体稀释法检测MIC,琼脂稀释法检测MBC,K-B纸片法检测土茯苓维生素C联合抗菌作用。结果土茯苓配方颗粒对铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌、粪肠球菌、肺炎克雷伯菌、洋葱伯克霍尔德菌的MIC50分别为25、1.56、12.5、25、0.78、6.25mg/mL;土茯苓维生素C复合纸片的抑菌圈均明显大于土茯苓配方颗粒纸片。结论土茯苓配方颗粒抗菌活性较强,联合使用维生素C可以增强其抗菌效能。
Objective： To observate the antibacterial activity of Smixlax glabra Particles on common clinical pathogent.Methods： The antibacterial activity about combination of Smixlax glabra Particles and vitamin C was assayed by K-B method.The minimum inhibitory and the minimum bactericidal concentrations respectively were tested using the dilution method.Results： The MIC50 of Smixlax glabra Particles on P.aeruginosa,E.coli,S.aureus,Enterococcus faecalis,Klebsiella Pneumoniae subsp.pneumoniae and Burkholderia cepacia were respectively 25mg/mL,1.56mg/mL,12.5mg/mL,25mg/mL,0.78mg/mL,6.25mg/mL.The acteriostatic circle about combination of Smixlax glabra Particles and vitamin C were significantly greater than that of the Smixlax glabra Particle.Conclusion： Smixlax glabra Particle has strong antibacterial activity.It plus vitamin C can enhance antibacterial efficacy of Smixlax glabra Particle.
出处
《中国中医急症》
2011年第12期1957-1958,共2页
Journal of Emergency in Traditional Chinese Medicine
基金
江苏省镇江市科技局社会发展项目(SH2006049)
关键词
土茯苓配方颗粒
最小抑菌浓度
药物敏感试验
最小杀菌浓度
Smixlax glabra Particle
Minimal inhibitory concentration
Drug sensitive test
Minimal bactericidal concentration
