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调节性T细胞的研究进展及临床应用

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摘要 人体调节性T细胞（Regulatory T cell,Treg）的主要作用为维持自身免疫耐受,调节机体对病原体和肿瘤的免疫应答,占正常人外周CD4＋T细胞的5%～10%,广泛存在于淋巴器官及非淋巴器官中。调节性T细胞数量和功能的降低导致自身免疫耐受消失从而产生自身免疫病,相反,调节性T细胞活性的增加会抑制内源性抗肿瘤反应而导致恶性肿瘤的发生。
作者 李青 邓琦
机构地区 天津市第一中心医院血液科
出处 《当代医学》 2011年第36期33-35,共3页 Contemporary Medicine
关键词 调节性T细胞 临床应用 自身免疫耐受 CD4+T细胞 淋巴器官 恶性肿瘤 自身免疫病 抗肿瘤反应
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献24

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二级参考文献32

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当代医学
2011年 第36期

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