摘要
目的研究卵巢癌组织中P37蛋白的表达,探讨猪鼻支原体感染与卵巢癌发生的关系。方法采用免疫组化法检测109例卵巢癌组织和30例正常卵巢组织中的P37蛋白表达情况。结果卵巢癌组织中P37蛋白阳性表达率为43.1%(47/109),正常卵巢组织的阳性表达率为0(0/30),两者相比差异具有统计学意义(P<0.001)。结论卵巢癌组织中存在猪鼻支原体的感染,卵巢癌的发生与支原体感染有一定的相关性。
Objective To detect P37 protein expression of Mycoplasma hyorhinis on ovarian cancer and the relationship between mycoplasma infection and ovarian cancer.Methods In this study,109 cases of ovarian cancer and 30 cases of normal ovarian tissues were used.Immunohistochemistry（IHC） was applied to analyze P37 protein.Results Mycoplasma hyorhinis P37 protein expression ratio was 43.1%（47/109） in ovarian cancer.But it was 0（0/30 cases） in the normal ovarian tissues.Ovarian cancers had a higher mycoplasma infection ratio than the normal ovarian tissue（P0.001）.Conclusion There was high mycoplasmal infection ratio in ovarian cancer tissues,Our data suggest mycoplasma infection have a possible function in ovarian cancer.
出处
《南昌大学学报（医学版）》
CAS
2011年第9期31-32,36,共3页
Journal of Nanchang University：Medical Sciences
