摘要
目的了解结核病患者单纯疱疹病毒的感染情况,探讨其可能对结核病病情的影响。方法采用金标免疫斑点渗滤法分别检测51例肺结核患者和30例正常健康人血浆单纯疱疹病毒感染的IgM和IgG。结果肺结核患者组HSV-IgM的阳性率为88.24%与对照组(66.67%)相比,差异有统计学意义(P<0.05);HSV-IgG的阳性率为80.39%,与对照组(70.00%)相比,差异无统计学意义(P>0.05);有肺炎表现者HSV-IgG的阳性率为61.11%,与无肺炎表现的患者组(90.91%)相比,差异有统计学意义(P<0.05);经统计学处理,HSV的活动性感染与病程、分期、痰涂片阳性无相关性(P>0.05)。结论肺结核患者存在较高的活动性单纯疱疹病毒感染,活动性单纯疱疹病毒感染与病情轻重有一定关系。
Objective To learn about tuberculosis patients with herpes simplex virus infection and explore the possible impact of TB disease. Methods To test IgG and IgM of 51 cases of patients with tuberculosis as well as 30 cases of normal plasma with herpes simplex virus infection respectively by using gold immune spots filtration meth- od. Results The HSV-IgM positive rate of the group of patients with tuberculosis was 88.24 % compared with that of the matched group（66.67 % ）, and the difference was statistically significant （P〈0.05）. However, the HSV--IgG positive rate was 80.39 % compared with that Of the matched group （70.00 % ） ,and the difference was statistically significant （P〈0.05）. The HSV--IgG positive rate of the patients with pneumonia performance was 61.11% compared with that of patients without pneumonia performance（90.91% ） and the difference was statistically significant（P〈0.05）. Through statistical processing it was affirmed that there was no relevance between the active infection of HSV and the course of disease, the stage, the positive of sputum smear（P〉0.05）. Conclusion The tuberculosis patients are more likely infected with active herpes simplex virus. There is some connection between active herpes simplex virus infection and the condition of illness.
出处
《济宁医学院学报》
2011年第6期413-415,共3页
Journal of Jining Medical University
关键词
结核病
单纯疱疹病毒
感染
Tuberculosis
Herpes simplex virus
Infection
