摘要
目的:提高前列腺炎症性肌纤维母细胞瘤(IMT)的诊治水平。方法:回顾性分析1例前列腺IMT患者的临床资料并复习相关文献。患者,男性,62岁,因反复排尿困难曾在当地医院诊断为"前列腺增生症",前后行两次前列腺电切术(TURP)。术后症状仍反复发作,故患者第1次来我院就诊,行TURP加经尿道膀胱肿瘤电切术(TUR-BT)。病检结果示:(膀胱)慢性炎症,区域性尿路上皮呈乳头增生伴轻度不典型增生,前列腺IMT。术后6个月,患者症状再次复发,第2次来我院就诊。泌尿系CT发现其膀胱内有一巨大肿块。结果:患者行腹腔镜下膀胱根治性切除术并盆腔淋巴结清扫+回肠膀胱术。病理学诊断为:复发性前列腺IMT并累及膀胱,无局部淋巴结转移。术后随访11个月,未见局部复发与远处转移。结论:前列腺IMT是一种罕见的交界性肿瘤,其临床诊断困难,主要依靠病理诊断。前列腺IMT有复发可能,并能累及膀胱。肿瘤体积大且多次复发者,应行根治性手术切除,术后应加强随访。
Objective ： To discuss the diagnosis and treatment of inflammatory myofibroblastic tumor （IMT） of the prostate. Methods： We retrospectively analyzed the clinical data of a case of IMT of the prostate and reviewed relevant literature. The patient was a 62-year-old man, who was twice referred to the local hospital for recurrence of dysuria. He was diagnosed as with benign prostatic hyperplasia （BPH） and twice underwent transurethral resection of the prostate （TURP）. But frequent recurrence of dysuria followed postoperatively, for which he came to our hospital and received another TURP and transurethral resection of the bladder tumor （TURBT）. Pathological findings showed chronic inflammation of the bladder, papillary hyperplasia with mild dysplasia in regional urothelia and IMT of the prostate. Six months later, the patient came again to our hospital for recurrence of dysuria. Computed tomo- graphy revealed a large mass in the bladder. Results： The patient underwent laparoscopic bladder radical resection and ileal conduit diversion, simuhaneously with pelvic lymph node dissection. The pathological examination confirmed it to be an IMT of the prostate with the bladder but not regional lymph nodes involved. An 11-month follow-up showed neither local recurrence nor distant metastasis. Conclusion ： IMT of the prostate is a rare borderline lesion, whose diagnosis is very difficult and mainly depends on pathological find- ings. IMT of the prostate is liable to recur and even invade the bladder. Radical resection is recommended for patients with large and recurrent tumors, and close follow-up is strongly warranted.
出处
《中华男科学杂志》
CAS
CSCD
北大核心
2011年第12期1108-1111,共4页
National Journal of Andrology
关键词
炎性肌纤维母细胞瘤
前列腺
膀胱
inflammatory myofibroblastic tumor
prostate
bladder
