摘要
目的 用干扰素与胸腺肽治疗慢性无症状HBV携带者,观察其对HBV复制指标的影响。方法 将146例慢性无症状HBV携带者随机分为三组。Ⅰ组应用干扰素冶疗,Ⅱ组应用胸腺肽治疗,Ⅲ组应用干扰素和胸腺肽治疗。治疗6个月后随访6个月,在不同时期检测HBV复制指标并比较其差异。结果 Ⅲ组疗效优于Ⅰ组和Ⅱ组(P<0.05及P<0.01),Ⅰ组与Ⅱ组间疗效无差异。结论 干扰素与胸腺肽联用可明显提高对HBV的抑制或清除。
Objective To observe the curative effects of applying interferon and thymic peptide in the treatment of chronic asymptomatic hepatitis B virus (HBV) carriers on the replication indices of HBV.Methods 146 cases of chronic asymptomatic HBV carriers were randomly classified into three groups.Interferon was ussed in Group One,thymic peptide in Group Two,and the combined use of both interferon and thymic peptide in Group Three.The HBV replication indices in different periods were detected and compared in the 6 months of follow-up survey after the 6-month treatment.Results The curative effects were found better in Group Three than those in Group One and Group Two.(P<0.05 and 0.01).There were no significant differences between Group One and Group Two.Conclusion The combined use of both interferon and thymic peptide can more effectively help to inhibit and clear HBV than the use of only one kind of drug.
出处
《临沂医学专科学校学报》
1999年第4期269-271,共3页
Journal of Linyi Medical College
