摘要
目的:探讨妊高征患者外周血红细胞免疫功能的变化和血浆TXB2水平的相关性。方法:应用放射免疫分析和免疫法对33例妊高征患者进行红细胞免疫功能和血浆TXB2检测,并与35名正常人作比较。结果:妊高征患者RBC-C3bRR水平明显降低(P<0.01),而血浆TXB2水平显著升高(P<0.01),RBC-C3bRR与TXB2水平呈显著负相关(r=-0.3628,P<0.05),RBC-ICRRR水平显著高于正常人组(P<0.01),与血浆TXB2水平呈明显正相关(r=0.4084,P<0.05)。结论:妊高征患者在免疫调节的紊乱、免疫功能低下与血浆TXB2有一定的相关性。
Objective To explore the relationship between changes of immunofuction status of peripheral blood red blood cells and plasma thromboxane B2（TXB2） level in patients with PIH.Methods RBC immunofunction status was studied with immunologic methods and plasma TXB2 Level was measured with RIA in 33 patients with PIH and 35 normal controls.Results Level of RBC-C3bRR was significantly lower and level of plasma TXB2 was markedly higher in the patients than those in controls（P0.01）,these two variable were significantly negatively correlated（r=-0.3628,P0.05）,the RBC-ICRRR level was significantly higher in the patients（P0.01） and was positively correlated with level of TXB2（r=0.4084,P0.05）.Conclusion There were disturbance of RBC immunoregulation with suppressed immune function and higher TXB2 levels in patients with PIH.
出处
《放射免疫学杂志》
CAS
2011年第6期636-637,共2页
Journal of Radioimmanology
关键词
妊高征
红细胞免疫功能
血栓素
B2
pregnancy induced hypertension（PIH）
red blood cell（RBC） immunofunction
thromboxane B2（TXB2）
