摘要
420例患者，分别外用皮康王霜、皮炎平霜、肤轻松霜等，或外用2种以上的皮质类固醇制剂，人均用药时间为2-31个月，人均用药量15-519g。用药后不仅使所有患者的原发皮肤病的病情加重，且出现如下副作用：红斑、干燥、脱屑420（100.0％），毛细血管扩张202例（48．09%），皮肤萎缩181例（43.09%），毛囊性炎性丘疹174例（41.42％），色素沉着154例（36.66％），粉刺102例（24.28％），多毛88例（20.95％），色素减退83例（19．76%），毛囊性脓疱32例（7.61％）等。对仍在外用皮质类固醇的396例予停药并对症施治，有273例获得成功。
Four hundred twenty patients were treated with topical corticosteroids, suchas cream pikangwang, cream piyanping, cream fuqingson, etc or more than two of thecorticosteroid preparations, The period of administration was ranged from 2 to 31 months,and the amount of drug usd l5 ~ 5l9g, personally. After application not only the aggra-vation of primary skin diseases in all of the patient, but also appeared the following sideeffects: erythema, dryness, desquamation in 420 cases(100% ), telangiectasis in 202cases(48. 09% ), skin atrophy in 181 cases (43. 09% ), folliculitis type papules in 174cases(41. 42% ), hyperpigmentation in 154 cases(36. 66% ), acne in 102 cases(24. 28% ), hypertrichosis in 88 cases(20. 95% ), hypopigmentation in 83 cases(19. 76% ) follicular pustules in 32 cases(7. 61 % ) etc. 396 patients discontinued thetopical application of corticosteroids and treated symptomatieally, 273 patients had suc-cessful results.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
1999年第6期353-355,共3页
Journal of Clinical Dermatology
关键词
皮质类固醇
外用
副作用
皮肤药
Corticosteroid Local application Adverse effects
