摘要
本文对采用益气活瘀法制成的胶囊治疗冠心病心绞痛120例患者进行疗效观察,同时观察其对血小板聚集性、血栓素B_2、血浆组织型纤溶酶原激活剂(t-PA)及其抑制剂(PAI)活性、超氧化物歧化酶、丙二醛含量及心电图、血流变的影响。结果表明益气活瘀组总有效率为86.7％,明显优于对照组(P <0.005),对气虚血瘀、气血两虚型疗效均明显优于对照组(P<0.01),临床症状较对照组明显改善。血小板功能和纤溶活性较治疗前有明显改善,其作用优于对照组(P<0.05～0.01);明显提高血清中SOD活性,降低MDA含量,作用明显优于对照组(P<0.05～0.01);心电图及血流变情况均有明显改善。由此说明益气活瘀是治疗冠心病心绞痛的有效方法。
120patients with coronary heart disease with angina pectoris treated with Chinese medicine capsule fromulated according to rule of tonifying qi and removing stasis of blood. the changes of PAg, TXB2, t - PA, PAI, SOD, MDA, EGG and hemorheology were observed at the same time. The results showed that the total effective rate of capsule group was 86.7% , which was much better than that of cortrol (P<0.05) .there was no difference between deficiency of qi and blood type and deficiency of qi and stasis of blood, the improvement of main symptoms and sign were more significant than that of control. The improvemert of PAg and t - PA were more obvious than that of control(P<0.05 - 0.01), SOD activity increased and MDA content decreased significantly in capsule group(p<0.05-0.01).the improvement of ECG and hemorheology was obvious.
All these suggested that tonifying qi and removing stasis of blood was the effective method for the treatment of coronary heart disease with angina pectorsis.
出处
《中国中医药科技》
CAS
1999年第6期356-358,共3页
Chinese Journal of Traditional Medical Science and Technology
