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不同区域骨密度值对原发性骨质疏松症诊断的影响 被引量:14

The Importance and Significance of Bone Mineral Density in the Difference Areas for the Diagnosis of Primary Osteoporosis
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摘要 目的分析受检区域骨密度(bone mineral density, BMD)值的差异对原发性骨质疏松症(osteoporosis, OP)诊断的影响。方法回顾在我院进行 BMD检查的 1233例患者,男 414例,女 819例;年龄20-89岁;除外内分泌、肿瘤等疾病及皮质激素治疗史人群。用双能X线骨密度仪(DEXA)对腰椎、髓部及全身进行扫描,测量不同部位的BMD值,采用计算机EXCEL软件进行统计学分析,计量资料进行均数 t检验。结果 L1~2 BMD值比 L2-4低,尤以 40岁以上的女性明显(P<0. 01),髓部BMD值以Ward三角处最低(P<0. 01)。结论腰椎退行性变的干扰影响椎体BMD值的真实性,髋部Ward三角处 BMD值的低下,反映该处骨小梁结构薄弱。 OP的诊断应参考受检区域不同部位的 BMD值,至少进行两个区域的BMD检查对OP的诊断才有意义。 Objective To analyze the significance of the difference of bone mineral density (BMD) in the examined areas for comfirmation of the diagnosis of primary osteoporosis. Methods The BMD in each part of lumbar spine, hip and whole body was investigated by Dual Energy X-ray Absorptiometry (DEXA) in 1 233 persons aged 20 -- 89 (414 males, 819 females). DPL^+ (LUNAR co USA) and EXCEL software were used for the analysis and comparison. Results The BMD in L_ 1 --2 was lower than L_ 2-4 especially after the ages of 40 in the females(P < 0. 01 ), and the BMD in Ward striangle area was the lowest among all other parts of hip (P < 0. 01 ). Conclusion The truthfulness of BMD in lumbar spine was changed by degeneration. The lower BMD in Ward striangle area indicated the weak structure in bone. The diagnosis of osteoporosis should refer to the BMD on any areas and any parts of the skeleton, and at lease two areas should be examined for significant conclusions.
出处 《中华骨科杂志》 CAS CSCD 北大核心 1999年第12期723-725,共3页 Chinese Journal of Orthopaedics
关键词 骨密度 骨质疏松 诊断 BMD Bone density Osteoporosis Diagnosis
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