摘要
目的:观察产后产褥感染者血清C反应蛋白(CRP)水平的动态变化。方法:根据是否发生产褥感染将380例孕产妇分为无产褥感染的对照组302例和产褥感染组78例,分别在产前1天、产后第1、3、5、7天采集静脉血,采用双抗体夹心法检测两组受试者不同时间点的血清CRP水平。结果:不同感染原因的产褥感染组受试者其血清CRP水平峰值相异,外阴炎最低,盆腔腹膜炎最高。两组受试者产后第1天血清CRP水平明显高于产前1天(P<0.05);对照组产后第3天血清CRP水平逐渐下降,至产后第7天与产前1天水平相近。产褥感染组血清CRP水平在产后第3天升高达峰值,产后第5天逐渐下降,产后第7天仍高于对照组(P<0.05)。结论:动态监测产妇血清CRP水平对防治产褥感染具有较好的临床价值。
Objective：To observe the dynamic change of serum C-reactive protein level in the patients with puerperal infection.Methods：380 pregnant women were divided into control group（without puerperal infection,302 cases） and puerperal infection group（78 cases）,their venous blood samples were obtained at one day before delivery,the first,third,fifth and seventh days after delivery,double-antibody sandwich method was used to detect the serum C-reactive protein levels at different time points in the two groups.Results：In puerperal infection group,the peak values of serum C-reactive protein among pregnant women with different causes of infection varied,the peak value of serum C-reactive protein among pregnant women with vulvitis was the lowest,while the peak value of serum C-reactive protein among pregnant women with pelvic peritonitis was the highest.In the two groups,the serum C-reactive protein levels on the first day after delivery were significantly higher than those at one day before delivery（P0.05）.In control group,the serum C-reactive protein level on the third day decreased gradually,the serum C-reactive protein level on the seventh day after delivery was similar to that at one day before delivery.In puerperal infection group,the serum C-reactive protein level on the third day after delivery peaked,then decreased gradually on the fifth day after delivery,the serum C-reactive protein level on the seventh day after delivery was still higher than that in control group（P0.05）.Conclusion：The clinical value of dynamic monitoring of serum C-reactive protein level among pregnant women is high.
出处
《中国妇幼保健》
CAS
北大核心
2011年第34期5317-5318,共2页
Maternal and Child Health Care of China
关键词
产妇
产褥感染
C反应蛋白
动态监测
Pregnant women
Puerperal infection
C-reactive protein
Dynamic monitoring
