摘要
Z-肉桂酰哌嗪类化合物具有保护大脑、恢复脑损伤后机能和促进记忆、学习的活性,而E型物具有抗心绞痛活性。显然。
Introduction of methyl, phenyl, acetylamino, or benzoylamino groups to theα-position of 4-(3, 4, 5-trimethoxycinnamoyl)-1-(pyrrolidinocarbonylmethyl) piperazinegave a series of α-substituted cinnamoyl piperazines, which was photoisomerized under theirradiation of sun light, tungsten-halogen lamp, or mercury lamp. The configurations ofthe products were assigned with ~1H NMR and UV.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
1990年第5期440-444,共5页
Chinese Journal of Organic Chemistry
基金
天然药物及仿生药物国家重点实验室资助课题
关键词
肉桂酰哌嗪
合成
光异构化
substitutent group
cinnamoyl
piperazine
photoisomerization
synthesis
