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Intensity-modulated Radiotherapy for Sinonasal Teratocarcinosarcoma

Intensity-modulated Radiotherapy for Sinonasal Te-ratocarcinosarcoma
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摘要 Surgical excision and postoperative radiotherapy are widely accepted therapeutic modalities for sinonasal teratocarcinosarcoma (SNTCS). Previous studies have shown that intensity-modulated radiation therapy (IMRT) is safe and effective for the treatment of some sinonasal malignancies. We hypothesize that use of IMRT for SNTCS may result in clinical benefits. We report here two cases of SNTCS that were treated by IMRT. One patient was given extensive IMRT involving elective neck irradiation. Follow-up examinations revealed no recurrence and metastasis 3.5 years after IMRT. Another patient simultaneously suffered from multiple systematical diseases and was administered involved-field radiotherapy. He was found to have a marginal recurrence during the follow up and eventually died 8 months after disease diagnosis. It was suggested in this study that appropriate use of IMRT for the treatment of SNTCS may achieve excellent local control. Surgical excision and postoperative radiotherapy are widely accepted therapeutic modalities for sinonasal teratocarcinosarcoma (SNTCS). Previous studies have shown that intensity-modulated radiation therapy (IMRT) is safe and effective for the treatment of some sinonasal malignancies. We hypothesize that use of IMRT for SNTCS may result in clinical benefits. We report here two cases of SNTCS that were treated by IMRT. One patient was given extensive IMRT involving elective neck irradiation. Follow-up examinations revealed no recurrence and metastasis 3.5 years after IMRT. Another patient simultaneously suffered from multiple systematical diseases and was administered involved-field radiotherapy. He was found to have a marginal recurrence during the follow up and eventually died 8 months after disease diagnosis. It was suggested in this study that appropriate use of IMRT for the treatment of SNTCS may achieve excellent local control.
机构地区 Cancer Center
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2011年第6期857-860,共4页 华中科技大学学报(医学英德文版)
关键词 sinonasal teratocarcinosarcoma RADIOTHERAPY head and neck cancer intensity-modulated radiation therapy paranasal sinus sinonasal teratocarcinosarcoma radiotherapy head and neck cancer intensity-modulated radiation therapy paranasal sinus
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参考文献21

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