摘要
目的比较单纯肝动脉栓塞化疗和肝动脉栓塞化疗联合三维适形放疗对原发性肝癌的疗效。方法 48例原发性肝癌患者,随机分为单纯TACE组和TACE联合3DCRT组,按照WHO肿瘤评定标准评价近期疗效,以3年内生存率为指标评价远期疗效。结果 TACE组24例患者中完全缓解(CR)0例,部分缓解(PR)13例,总有效率(CR+PR)为54.17%。TACE联合3DCRT组24例患者中完全缓解(CR)1例,部分缓解(PR)16例,总有效率(CR+PR)为70.83%。TACE组1、2、3年生存率分别为58.33%、33.33%和16.67%;TACE联合3DCRT组1、2、3年生存率分别为79.17%、54.17%和25.00%。结论 TACE联合3DCRT组疗效优于TACE组。
Objective To compare the therapeutic effects of transcatheter arterial chemoembolization（TACE） and TACE combined with three dimensional radiation（3-DCRT） in the treatment of patients with primary hepatocellular carcinoma（HCC）.Methods 48 patients were randomly divided into TACE and TACE＋3-DCRT.The short term effect was evaluated according to WHO tumor evaluation standard and long term effect by three-year survival rate.Results The total response（CR＋PR） in TACE was 54.17% and in TACE＋3-DCRT was 70.83%.The overall survival rates at 1,2 and 3 years were 58.33%,33.33% and 16.67% in TACE,and 79.17%,54.17%,and 25.00% in TACE＋3-DCRT group.Conclusion TACE combined with 3-DCRT is superior to TACE alone in the treatment of patients with primary hepatocellular carcinoma.
出处
《实用癌症杂志》
2011年第6期634-636,共3页
The Practical Journal of Cancer
关键词
原发性肝癌
肝动脉栓塞化疗
三维适形放疗
Primary hepatic carcinoma
Transcatheter hepatic arterial chmoembolization
Three-dimensional conformal radiotherapy
