摘要
目的探讨氩氦刀靶向冷冻联合动脉内栓塞化疗对晚期非小细胞肺癌的临床疗效。方法将78例ⅢB和Ⅳ期非小细胞肺癌患者分为两组:一组(40例)行氩氦刀靶向冷冻消融+靶动脉栓塞化疗治疗,另一组(38例)行单纯靶动脉栓塞化疗,观察比较两组近期疗效、生存期、生存质量、症状缓解及免疫功能等多方面的变化。结果治疗组有效率为82.5%,对照组为47.5%;中位生存期治疗组为18个月,对照组为12个月,两组比较差异有显著性意义(P<0.01);在生存质量、症状缓解及免疫功能方面,均提示治疗组好于对照组。结论 CT引导下经皮穿刺氩氦刀冷冻消融联合靶动脉栓塞化疗,对中晚期非小细胞肺癌的疗效优于靶动脉栓塞化疗。
Objective To investigate the efficacy of Ar-He Cryosurgery combined with TACE for advanced non-small cell lung cancer.Methods A total of 78 patients with stage ⅢB and Ⅳ non-small cell lung cancer were randomly separated into two groups.Patients in the first group（40 cases） were treated by TACE after Ar-He Cryosurgery and patients in the second group（38 cases） underwent Ar-He Cryosurgery alone.The short term effect,survival,quality of life,symptoms and immune functions were compared in the two groups.Results The response rate in the treatment and control groups was 82.5% and 47.5%,respectively;and the median survival time was 18 months and 12 months,which were significantly different in the two groups（P0.01）.The quality of life,improvement of the symptoms and the enhancement of the immune functions were significantly better in the treatment group than that in the control group.Conclusion Ar-He Cryosurgery combined with TACE is more effective than TACE alone in the treatment of patients with advanced non-small cell lung cancer.
出处
《实用癌症杂志》
2011年第6期613-616,共4页
The Practical Journal of Cancer
关键词
栓塞化疗
氩氦刀
原发性
肺肿瘤
Chemoembolization
Cryosurgery
Primary
Lung neoplasms
