摘要
慢性阻塞性肺疾病(COPD)常合并慢性心力衰竭,虽然肾上腺素β受体(β受体)阻滞药作为治疗慢性心力衰竭的基础药物,但长期被认为是治疗COPD的禁忌证。近来有研究报道,长期使用心脏选择性β受体阻滞药可降低COPD患者的死亡率并提高生活质量。本文就COPD患者中应用β受体阻滞药的研究进展进行综述。
Chronic obstructive pulmonary disease (COPD) is always combined with chronic heart failure. As the cornerstones of therapy for chronic heart failure, beta-adrenoceptor blockers (beta-blockers) are contra-indicated in COPD. Recent studies showed that chronic administration of cardioselective beta-blockers could decrease mortality and improve quality of life in COPD patients. This paper reviewes the research advancement and dispute of beta-blockers on patients with COPD.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2011年第11期815-819,共5页
Chinese Journal of New Drugs and Clinical Remedies