摘要
目的研究辛伐他汀在急性缺血性脑卒中的疗效。方法采用单盲随机安慰剂对照方法将64例急性缺血性脑卒中患者随机分为治疗组和对照组。所有患者在控制血压及血糖基础上均常规予以甘露醇降颅压及阿司匹林抗血小板治疗。治疗组32例予辛伐他汀40mg每晚1次,对照组32例予以安慰剂治疗,通过观察两组治疗前后临床神经功能缺损的变化进行比较。结果治疗组在治愈率及总有效率较对照组差异有统计学意义(P<0.01)。结论辛伐他汀在急性缺血性脑卒中的治疗中有显著效果。
Objective To research simvastatin in acute ischemic cerebral apoplexy effect. Methods Single-blind, placebo-controlled randomized method will be 64 cases of acute ischemic stroke patients were randomly divided into treatment and control groups. All the patients in the control of blood sugar and blood pressure were based on the conventional mannitol be reduced intracranial pressure and Aspirin anti-platelet therapy. Group therapy to 32 patients with Simvastatin 40 mg qn, 32 cases in the control group to placebo treatment. By observing two groups before and after the clinical treatment of neurological changes in the comparison. Results The cure rate in the treatment group and the total effective were better than the control group significantly （P 〈 0. 01 ）. Conclusion Simvastatin in acute ischemic cerebral apoplexy treatment in a significant effect.
出处
《中国实用医药》
2011年第30期20-21,共2页
China Practical Medicine
