摘要
目的:了解右江民族医学院附属医院药品不良反应(ADR)发生的规律与特点。方法:收集2009年1—12月各科室上报的ADR报告226例,根据国家食品药品监督管理局ADR监测中心制定标准,进行描述、因果关系分析与评价、汇总、分级以及统计分析。结果:226例ADR报告中,≥70岁的患者ADR发生率高,为59例,占26.11%,其次是50～69岁58例,占25.66%;静脉给药途径ADR发生率最高,为196例,占86.73%;抗感染药致ADR发生率最高,为105例,占46.46%;最常见的ADR临床表现为皮肤及其附件损害,为139例,占59.66%。结论:临床应合理应用抗菌药物和静脉注射药物,以减少ADR的发生。
OBJECTIVE： To probe into the characteristics and regularity of the adverse drug reactions （ADRs） occurred in Guangxi Youjiang Medical College of Nationalities Affiliated Hospital. METHODS： A total of 226 ADR case reports submitted by our hospital between Jan. and Dec. in 2009 were described, evaluated regarding the causal relation, graded and statistically analyzed in accordance with the criteria established by State ADR Monitoring Center. RESULTS： Of the 226 ADR cases, patients aged ≥70 showed the highest incidence（59 cases/26. 11% ） followed patients aged 50-69 years （58 cases/25. 66% ）; 196 （86. 73% ） were induced via intravenous route; 105 （46. 46% ） were induced by anti-infective drugs. The ADR manifested in most eases as lesions of skin and its appendants （139 cases/59. 66% ）. CONCLUSION： Antibiotics and intravenously administered drugs should be used rationally to reduce ADR incidence.
出处
《中国医院用药评价与分析》
2011年第11期1040-1042,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
抗菌药物
报告
分析
Adverse drug reaction
Antibiotics
Report
Analysis
