摘要
目的:为了研究男性非淋患者CT DNA和UU DNA流行病学特征。方法:FQ-PCR用于定量检测男性生殖道样本中的UU DNA和CT DNA。结果:非淋病原体感染率UU DNA(26.64%,517/1941)显著高于CT DNA(9.26%,177/1911)(χ2=196.78,P=1.05E-44),而载量比较显示UU DNA(4.47±1.36)显著低于CT DNA(4.72±1.85)(t=4.913,P=9.47E-7);UU DNA阳性率逐年上升(r=+0.87,p=0.028),载量逐年下降(r=-0.75,P=0.020);CT DNA阳性率无统计学变化(r=+0.48,P=0.19),载量逐年下降(r=-0.88,P=0.0016)。结论:UU是男性非淋菌性尿道炎的主要病原体,CT急性感染的比例高于UU,UU感染流行有增加的趋势,CT感染趋势较为稳定。
Objective：To study the epidemiological characteristics of UU DNA and CT DNA in male patients with non-gonococcal urethritis.Methods： FQ-PCR was used for the quantitative detection of UU DNA and CT DNA in the sample of the male patients with non-gonococcal urethritis.Results： The positive rates of UU DNA（26.64%,517/1941） was higher than CT DNA（9.26%,177/1911）（χ2=196.78,P=1.05E-44）,the load of UU DNA（4.47±1.36）was lower than the CT DNA（4.72±1.85）（t=4.913,P=9.47E-7）;The positive rates of UU DNA increased（r=＋0.87,P=0.028）while the load went down（r=-0.75,P=0.020） year by year;The positive rates of CT DNA has no difference in statistics（r=＋0.48,P=0.19） while the load went down year by year（r=-0.88,P=0.0016）.Conclusion： UU was the main pathogen of non-gonococcal urethritis for man.The proportion of acute infection by the CT were higher than that by the UU,the infection rate of the UU increased while that of CT was stable.
出处
《中国卫生检验杂志》
CAS
2011年第11期2701-2702,2776,共2页
Chinese Journal of Health Laboratory Technology
