摘要
目的通过检测比较肝硬化患者和健康人血小板参数,了解肝硬化患者血小板参数变化及其临床意义。方法采用血细胞分析仪对肝硬化86例进行血小板分布宽度、平均血小板体积、血小板计数的相关检查。并进一步检测肝硬化出血组与非出血组以及肝硬化Child分级A级、B级、C级组的PLT、MPV、PWD。结果发现较对照组肝硬化患者PLT、MPV显著降低(P<0.01),PDW显著升高(P<0.05)。肝硬化出血组与非出血组PLT、MPV、PWD比较亦有明显差异(P<0.01)。随着肝功能的下降,PLT、MPV随之下降。结论肝硬化患者血小板参数检测可以间接反映血小板的功能变化,判断有无出血倾向,对指导临床治疗及判断预后都有重要意义。
Objective To investgate the changes and clinical significance of platelet parameters in patients with cirrhosis by analyzing the data of platelet parameters between patients with cirrhosis of liver and healthy people. Methods 86 patients with cirrhosis were divided into two groups as bleeding group and unbleeding group, and three groups as Child Classification into A, B and C to test PLT, MPV and PDW. Results The PLT and MPV in patients with cirrhosis were obviously lower（ P 〈 0. 01 ）, meanwhile PDW was obviously higher（ P 〈 0.05 ）, the three in- dexes were significantly different in both bleeding and unbleeding groups（P 〈0.01 ） ,PLT and MPV were lower as the ALT got worse. Conclu- sion The platelet parameters can tell us the platelet function of patients with cirrhosis of liver, and remind us the tendency of bleeding, which is really very important for our clinical trearment and prognosis.
出处
《中外医学研究》
2011年第33期9-11,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
肝硬化
血小板计数
血小板功能
Cirrhosis
Platelet parameters
Platelet function
