摘要
低温(4±0.5℃)饲养的大鼠与室温者相比;1.受冷大鼠甲状腺肥大,其重量与体重之比值增加,血清甲状腺素(简称T_4)下降,3,5,3′一三碘甲腺原氨酸(简称T_3)升高,摄食量增加,两周后直肠温度回升到正常水平。2.补充核黄素(6.0mg/kg饲料)可使受冷大鼠血清T_4升高,并有缩短T_4恢复到正常水平时间之趋势。3.增加核黄素供给量对受冷大鼠血清T_3浓度无明显影响。提示,增加核黄素供给量可能对促进机体冷适应有一定作用。
In order to evaluate the effect of riboflavin on thyroid hormone levels in the blood of rats during cold exposure, male adult rats were divided randomly into six or eight groups. The group 1,2,5 and 6 were supplemented with 1.5mg riboflavin per kg basal diet, but the group 3, 4, 7 and 8 with 6.0mg riboflavin per kg basal diet. The group 1, 3, 5 and 7 were kept at the cold room (4±0.5) and the group 2,4,6 and 8 at room temperature. The results revealed that supplementation of riboflavin to cold exposed rats could raise the lowered T4 concentration of serum and shorten the time of T4 returned to its original levels. Therefore, riboflayin could hasten cold acclimatization of organism.
出处
《营养学报》
CAS
CSCD
北大核心
1990年第3期323-327,共5页
Acta Nutrimenta Sinica
关键词
核黄素
甲状腺素
大鼠
冷适应
riboflavin rat T_4 T_5 cold acclimatization
