1Barbalat R, Ewald SE, Mouchess ML, et al. Nucleic acid recognition by the innate immune system [J]. Annu Rev Immunol,2011,29:185 -214.
2Paludan SR, Bowie AG, Horan KA, et al. Recognition of herpesviruses by the innate immune system [J]. Nat Rev Immunol,2011,11 (2): 143-154.
3Casanova JL, Abel L, Quintana-Murci L. Human TLRs and IL-1Rs in host defense: natural insights from evolu- tionary, epidemiological, and clinical genetics [J]. Annu Rev Immunol,2011,29:447-491.
4Watanabe A, Tatematsu M, Saeki K, et al. Raftlin is in- volved in the nucleocapture complex to induce poly(I:C)- mediated TLR3 activation [J]. J Biol Chem,2011,286(12): 10702-10711.
5Jiang Z, Zamanian-Daryoush M, Nie H, et al. Poly(I-C)-in- duced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1- TAB2-PKR[J]. J Biol Chem,2003,278(19):16713-16719.
6Kuznik A, Bencina M, Svajger U, et al. Mechanism of endosomal TLR inhibition by antimalarial drugs and imi- dazoquinolines[J]. J Immunol,2011,186(8):4794-4804.
7Hattermann K, Picard S, Borgeat M, et al. The Toll-like receptor 7/8-1igand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis [J]. FASEB J,2007, 21(7):1575-1585.
8Forsbach A, Nemorin JG, Montino C, et al. Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses [J]. J Immunol,2008, 180(6):3729-3738.
9Takeda S, Miyazaki D, Sasaki S, et al. Roles played by tolMike receptor-9 in corneal endothelial cells after her- pes simplex virus type 1 infection [J]. Invest Ophthalmol Vis Sci,2011,52(9):6729-6736.
10Krug A, French AR, Barchet W, et al. TLR9-dependent recognition of MCMV by IPC and DC generates coordi- nated cytokine responses that activate antiviral NK cell function[J]. Immunity,2004,21(1): 107-119.
6Macpherson AJ, Uhr T. Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria [ J ]. Science, 2004, 303(5664) : 1662-1665.
7Guamer F, Malagelada JR. Gut flora in health and disease [ J ]. Lancet, 2003, 361(9356): 512-519.
8Aziz Q, Dore J, Emmanuel A, et al. Gut micmbiota and gastroin- testinal health: current concepts and future directions[ J] . Neuro- gastroenterol & Motility, 2013, 25( 1 ) : 4-15.
