摘要
目的:观察高压氧治疗早期急性脑梗死的临床疗效。方法:93例急性脑梗死患者按来诊前病程和神经功能缺陷评分,随机分为高压氧Ⅰ组(病程为24小时内,31例),高压氧Ⅱ组(病程为2～3天,31例)和常规药物组(病程24小时内15例,2～3天16例,共31例)。常规药物组给予5％葡萄糖250 ml加入胞二磷胆碱0.5克,每日一次静滴;脑复康0.8克,每日三次口服,10天为一疗程,共2个疗程。结果:临床症状和神经功能的改善,高压氧组均优于常规药物组,尤以高压氧Ⅰ组为明显(P<0.01)。结论:高压氧治疗脑梗死能够减轻脑组织缺氧、缺血,阻止急性脑梗死继发性神经元损伤,改善临床症状,尤其是早期高压氧治疗,效果更好。
Objective: To observe the effects of hyperbaric oxygenation in the treatment of acute cerebral infarction of early stage. Method: 93 patients with acute cerebral infarction were divided into three groups randomly according to th course of the disease and the scale of neurological function defects, hyperbaric oxygenation group Ⅰ(n=31, the course less than 24 hours), hyperbaric oxygenation group Ⅱ (n=31, the course between 48 to 72 hours), and the control(n=31, including 15 patients which the course less than 24 hours, and 16 patients which the course between 48 to 72 hours). 0.5 gram of citicoline added to 250 ml of 5% dextrose, iv drip, gd, and 0.8 gram of piracetam, PO, tid, in the control patients for 2 continuing ten days. Result: Clinical symptoms and scale of neurological function defects were dramatically improved in hyperbaric oxygenation groups, particularly in hyperbaric oxygenation group Ⅰ, than in the control(P<0.01). Conclusion: Hyperbaric oxygenation can alleviate the hypoxia and ischemia of brain, and further prevent secondary neuron injuries of the acute infarction, and improve the symptoms, especially treated with hyperbaric oxygenation as early as possible.
出处
《岭南急诊医学杂志》
2000年第3期118-119,共2页
Lingnan Journal of Emergency Medicine
关键词
高压氧
脑梗死
神经元损伤
hyperbaric oxygenation
cerebral infarction
neuron injury
