摘要
目的:探讨麻醉和血管扩张药控制性降压于鼻内窥镜手术的临床疗效。方法:50例择期实施鼻窦内窥镜手术且无手术禁忌证患者随机分为两组,分别施行瑞芬太尼-丙泊酚复合麻醉控制性降压(R组)和硝普钠血管扩张控制性降压(S组)。结果:两组在降压诱导时间,降压时间,血压恢复时间,术中各时间点动脉压和心率差异均无统计学意义(P>0.05);除40 min时间点之外,术中各时间点手术野评分差异均无统计学意义(P>0.05);R组在总手术时间、总出血量及不良反应率均显著低于S组(P<0.05)。结论:瑞芬太尼-丙泊酚复合麻醉控制性降压,能有效的控制鼻窦内窥镜手术的血压,减少术中出血,获得良好手术视野评分,取得鼻窦内窥镜手术的满意临床疗效。
Objective：To compare the clinical effects of anesthetic controlling hypotension and vasodilator controlling hypotension in endoscopic sinus surgery.Methods：50 patients undergoing selective endoscopic sinus surgery without surgical contraindications were randomized into two groups,25 cases per group.The group R was performed the anesthetic controlling hypotension with propofol combined remifentanil and the group S received vasodilator controlling hypotension with sodium nitroprusside.Results：There were no significant differences between R group and S group on the parameters of hypotension inducing time,hypotension period,blood pressure recovering time,MAP and HR at various time points（P0.05）.The scores of surgical field at all time points had no significant difference except a time point of 40min（P0.05）.Significant decrease of total operation time,total bleeding volume and adverse reaction rate were observed in the group R compared with the group S（P0.05）.Conclusion：Utilizing anesthetic controlling hypotension with combining remifentanil and propofol can effectively control the blood pressure,decrease intraoperative bleeding and obtain the better surgical field scores in endoscopic sinus surgery with satisfactory clinical effects.
出处
《现代医药卫生》
2011年第21期3232-3234,共3页
Journal of Modern Medicine & Health
关键词
鼻窦内窥镜手术
控制性降压
瑞芬太尼
丙泊酚
硝普钠
Endoscopic sinus surgery
Controlled hypotension
Remifentanil
Propofol
Sodium nitroprusside
