摘要
目的研究分析不同年度耐甲氧西林金黄色葡萄球菌（MRSA）的临床感染情况及耐药性。方法收集2008年1月至2010年12月本院微生物室分离的金黄色葡萄球菌,采用Phoenix-100全自动细菌鉴定药敏系统进行药物敏感试验,经仪器判定苯唑西林耐药的菌株为MRSA。结果 3年共分离出金黄色葡萄球菌菌株1 048株,其中MRSA 793株,占金黄色葡萄球菌总数的75.7%,2008~2010年分别为63.3%、72.7%、81.5%。MRSA对多种药物耐药,但对万古霉素、利奈唑胺、甲氧苄氨嘧啶、奎奴普丁/达福普汀、替考拉宁、呋喃妥因有较好的敏感性,无万古霉素、利奈唑胺耐药菌株出现。结论近3年来北京航天总医院的MRSA的分离率逐步增高,应加强监测,并为临床合理使用抗菌药物提供必要的实验室依据,以利于医院MRSA感染的控制。
Objective To analyze the antimicrobial resistance and clinical infection monitoring of methicillin-resistant staphylococcus aureus（MRSA） isolated from clinical samples from 2008 to 2010.Methods Staphylococcus aureus and MRSA were collected,and Phoenix 100 fully automated bacteria identification system was applied to the identification of bacteria and drug sensitivity test.Results A total of 1 048 strains of staphylococcus aureus were collected in 3 years,in which 793 were MRSA（75.7%）.Antimicrobial sensitivity test showed that MRSA was resistant to most antibiotics,but quite sensitive to Vancomycin,Linezolid,Trimethoprim,Quinupristin/dalfopristin,Teicoplanin and Nitrofurantoin.No strain resistant to Vancomycin or Linezolid was found.Conclusion MRSA have increased in the past 3 years in our hospital.It is of great value for monitoring the antimicrobial resistance and find out nosocomial infection of MRSA.
出处
《检验医学与临床》
CAS
2011年第21期2577-2578,2580,共3页
Laboratory Medicine and Clinic
关键词
耐甲氧西林金黄色葡萄球菌
金黄色葡萄球菌
耐药性
methicillin-resistant staphylococcus aureus
staphylococcus aureus
drug resistance
