老年原发性高血压患者心率与动态血压、左心室肥厚、血脂的相关性被引量：11

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摘要目的探讨老年原发性高血压(EH)患者静息心率(RHR)与动态血压、左心室肥厚及血脂的关系。方法对158例EH患者(按RHR水平分三组:RHRⅠ组<70次/min;70次/min≤RHRⅡ组<80次/min;RHRⅢ组≥80次/min)和同期129例正常健康体检老年人(对照组)测定RMR、血脂,并做动态血压及超声心动图检查,进行分组研究。结果①EH患者RHR显著高于正常对照组(P<0.05)。②按RHR水平分三组,组间动态血压参数比较:RHRⅢ组的24 h、白昼、夜间平均收缩压及脉压(TSBP、dSBP、nSBP;TPP、dPP、nPP)均高于RHRⅡ、RHRⅠ组,差异有统计学意义(P<0.05);而24 h、白昼、夜间平均舒张压(TDBP、dDBP、nDBP)的差异无统计学意义(P>0.05)。③三组患者左室后壁厚度(LVPW)、室间隔厚度(IVST)、左室舒张末期内径(LVDD)、左室射血分数(IVEF)和左室心肌重量指数(LVMI)差异有显著性(P<0.05),且随着RHR增加LVPWI、VST及LVMI增加,而IVEF降低。④三组患者血脂水平比较有显著性差异(P<0.05),且随RHR增加血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)水平升高,而高密度脂蛋白(HDL-C)水平降低。结论老年EH患者RHR与SBP、PP、血脂代谢异常及靶器官损害相关。

作者张强乔鹏杨丽红

机构地区郑州大学第二附属医院心内科郑州大学基础医学院生理教研室

出处《中国老年学杂志》 CAS CSCD 北大核心 2011年第20期3894-3896,共3页 Chinese Journal of Gerontology

关键词老年原发性高血压静息心率左心室肥厚血脂

分类号 R544.11 [医药卫生—心血管疾病]

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参考文献4

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