摘要
目的综合比较、评价甲状腺片的质量。方法运用高效液相色谱测定甲状腺片中3,3’,5-三碘甲状腺原氨酸和四碘甲状腺原氨酸的含量,并运用MATLAB软件对甲状腺片的质量进行聚类分析。结果含量测定与聚类分析相结合评价甲状腺片的质量,判断结果符合实际情况。结论该方法准确、可行,可作为甲状腺片的质量控制与评价的一种直观,合理、有效的技术手段。
Objective To compare and appraise the quality of thyroid tablets. Methods To determine the contents of liothyronine and levothyroxine in thyroid tablets by HPLC, to utilize MATLAB software to evaluate the quality of them. Results In combination of the contents and tcluster analysis to evaluate the quality of thyroid tablets, and the results showed that is accorded with reality. Conclusion This method was accurate and reliable, and it was apparent, credible and efficient method for quality evaluation of thyroid tablets.
出处
《中国医药科学》
2011年第20期24-25,52,共3页
China Medicine And Pharmacy
关键词
甲状腺片
HPLC
含量测定
聚类分析
Thyroid tablets
HPLC
Content determination
Cluster analysis
