摘要
目的:探讨我院2008-2010年短稳杆菌的感染和耐药情况,为临床预防和治疗短稳杆菌的感染提供依据。方法:用WHONET5.5软件,对我院近三年短稳杆菌的感染和耐药情况进行分析。结果:2008-2010年短稳杆菌的感染率虽然没有上升,但是它的耐药性却连续三年增强,特别是对对氨基糖甙类(妥布霉素、庆大霉素、阿米卡星)、头孢菌素类(头孢他啶、头孢曲松、头孢噻肟、头孢吡肟)和β-内酰胺类(安曲南)的耐药性大幅增强,2010年对上述药物的耐药性基本都超过了70%;相对而言,对左旋氧氟沙星、替卡西林/克拉维酸、哌拉西林、亚胺培南相对较为敏感,最高的耐药率只有33.3%,但是对亚胺培南的耐药性也逐渐增强,耐药率从13.3%上升至33.3%;痰液标本是短稳杆菌的重要来源,73.4%的短稳杆菌来源于患者的痰标本,在所有的送检痰标本中短稳杆菌的分离率为0.56%;短稳杆菌主要分离自10岁以下儿童和60岁以上老年人,感染的科室主要分布于小儿内科11例、呼吸内科12例、感染科4例、监护室4例、神经内科4例、血液病科4例,其余科室分有很少。结论:短稳杆菌三年来感染率虽然没有增加,但耐药性却又大幅度的提高,这种现象应引起重视,相关部门应采取有效措施,防止这种现象的蔓延。
Objective To study infection frequence and drug resistance of Empedobacter brevis in order to offer evidences of Empedobacter brevis infection to doctors and help to prevent and therapy Empedobacter brevis infection. Method Analyze infection frequence and drug resistance of Empedobacter brevis during 2008-2010 using WHNETS.5 software. Results Infection frequence of Empedobacter brevis didn＇t go on from 2008 to 2010, but drug resistance of Empedobacter brevis were going on, especially resistance to the following drugs became more and more serious as tobramycin, gentamiein, amikacin, cefepime, Ceftazidime, Ceftriaxone, Cefotaxime, Aztreonam. rate of resistance to the above drugs were super 70% in 2010; Empedobacter brevis was sensitive to tiearcillin-clavulnic acid, Levofloxacin, and imipenem comparing with the above drugs, only is the highest drug resistance rate 33.3%, but drug resistance to imipenem of Empedobacter brevis were going on from 2008 to 2010; 73.4% of Empedobacter brevis were mostly isolated from sputum, and 0.56% of suptum of patients contained Empedobacter brevis; Empedobacter brevis often trespass the under ten years older and the above sixty years older; the departments to be easy to be trespassed by Empedobacter brevis were child internal medicine, respiration internal medicine, infection medicine, nerve internal medicine, ICU and blood internal medicine, the few other departments were trespassed. Conclusion Infection frequence of Empedobacter brevis didn＇t go on from 2008 to 2010, but resistance to the antibiotics that are often used was going on, medical departments should take steps to control the drug resistance of Empedobacter brevis
出处
《实用医学杂志》
CAS
北大核心
2011年第21期3960-3962,共3页
The Journal of Practical Medicine
关键词
短稳杆菌
感染率
耐药性
Empedobacter brevis
Infection frequence
Drug resistance
