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肝癌高危人群的随访监测及小肝癌的早期筛选 被引量:1

The Follow-up Monitoring and Early Screening of Small Hepatocellular Carcinoma for High Risk Group of Hepatocellular Carcinoma
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摘要 目的为期从肝癌高危人群中筛选出早期肝癌,以提高诊疗效果并收集临床组织标本应用于后续实验研究.方法收集360例患有慢性肝病的中年人群的病例,划定为肝癌高危人群,通过定期的血清学检查及影像学检查对其进行系统的随访监测.结果对照肝癌组和随访肝癌组四项血清学标志物的水平明显高于肝炎后肝硬化组,差异具有统计学意义(P<0.05).结论 AFP,AFU,γ-GT,AFPL3可以作为肝癌高危人群的随访监测及小肝癌的早期筛选. Objective Primary hepatocellular carcinoma treatment and prognosis and occur at different stages of development are very relevant,early diagnosis and treatment of small hepatocellular carcinoma after 5-year survival rate was significantly higher than in advanced liver cancer,the probability for liver cancer higher in patients with close monitoring of the population has important implications.Methods We collected 360 middle-aged patients with chronic liver disease cases,and classified them as high risk of liver cancer.Then we follwed up them by regular serological tests and imaging tests,so as to screen early stage liver cancer,and improve clinical results.Result The levels of serologic markers in hepatocellular carcinoma group and hepatocellular carcinoma follow up group were higher than posthepatitic cirrhosis group(P0.05).Conclusion AFP,AFU,γ-GT,AFPL3 can be serologic markers in follow-up monitoring and early screening hepatocellular carcinoma in high risk group.
出处 《昆明医学院学报》 CAS 2011年第9期71-76,82,共7页 Journal of Kunming Medical College
关键词 肝癌 随访 监测 Hepatocellular carcinoma Follow-up Monitoring
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