摘要
重症急性胰腺炎是一种起病急、进展快、并发症多、病死率高的急腹症.常常由于并发多器官功能障碍综合征而造成患者死亡,病死率国外近期报道仍高达22.7%,我国报道21世纪初期的病死率也达15.60%-23.77%.究其原因,主要是其发病机制尚未完全阐明,导致治疗观点和治疗方案摇摆不定.本文阐述其发病机制研究进展,旨在探讨重症急性胰腺炎发病机制的复杂性,提高治疗效果.
Severe acute pancreatitis （SAP） is an acute abdominal disease that is characterized by sudden onset, quick progression, many complications and high mortality. Multiple organ dysfunction syndrome （MODS） is still regarded as the main cause of death in SAP patients. Nowadays, the mortality rate for patients with SAP in developed countries is 22.7%. In the early 21st century, the mortality reached 15.60%-23.77% in China's Mainland. However, the etiology, pathogenesis and pathophysiology of SAP remains unclear, resulting in puzzle or perplexity in choosing and developing treatment strategies for SAP. This paper reviews recent progress in understanding the pathogenesis of SAP.
出处
《世界华人消化杂志》
CAS
北大核心
2011年第23期2421-2425,共5页
World Chinese Journal of Digestology
