摘要
目的:观察低分子肝素(LMWH)对小儿原发性肾病综合征(PNS)的临床疗效。方法:将60例小儿PNS分为LMWH治疗组和对照组即常规治疗组,予以比较。结果:LMWH治疗组较对照组4周后血清白蛋白明显增高,总胆固醇明显下降(P<0.01),尿蛋白明显下降,尿蛋白转阴时间明显缩短(P<0.05)。结论:LMWH治疗后可明显改善小儿PNS的高凝状态,对其疾病的尽快缓解有重要意义,且副作用少,出血风险小,其安全性值得临床推广使用。
Objective：Observing the clinical effects of nadroparin calcium（LMWH） functioning on children primary nephrotic syndrome（PNS LMethods：Making a comparison in 60 samples which divided in to LMWH treating group and normal trcating group. Results：LMWH treating group increase in the amount of seralbumin and obviously found the descending of cholesterol（P〈.0.01） and descending of urin protein,and also the shortening of the integration time of urn＇in protein（P〈0.05） with the comparison to normal treating group after 4 weeks,Conclusinn：LMWH can obviously improve the 11ypercoagulability of Children PNS with less side effect and less risk of Needing.It is highly rrated in the clinical treatment because of its high safety.
出处
《中国医药导刊》
2011年第8期1380-1381,共2页
Chinese Journal of Medicinal Guide
关键词
肾病综合征
低分子肝素
高凝状态
Nephroiic syndrome：Nadroparin calcium
Hypercoagulability
